In Strategy Web 2021, you may get the following error after clicking Wrangle during the data import process, even though port 3333 is open on the Intelligence Server machine.
Encountered error when wrangling your data.
Connection times out: connect

A possible cause of this error is that HTTPS is enabled for the Refine Server but not properly configured.
Disable HTTPS for the Refine Server:
[Computer\HKEY_LOCAL_MACHINE\SOFTWARE\Wow6432Node\MicroStrategy\Refine Server].
enableHttpsregistry item.
If HTTPS is needed for the Refine Server, you can follow this documentation to enable HTTPS connection between the Refine Server and Web Server.