SUMMARY
This issue has been classified as a machine specific issue by Strategy. Correcting DCOM permissions on the Enterprise Manager Data Loader Service account can fix the issue.
SYMPTOM
In Strategy Enterprise Manager 9.x, scheduled data load does not kick off even when the Strategy Enterprise Manager data load service is running. From the Windows task manager, it is verified that the MAEMETLS.exe process is running. Also, the registry key HKEY_LOCAL_MACHINE\SOFTWARE\Wow6432Node\MicroStrategy\Enterprise Manager\Schedule is populated correctly as per the settings chosen on the Strategy Enterprise Manager console. It is also verified that DCOM is enabled on the machine.
However, the following error is seen in the Windows Event log:

The machine-default permission settings do not grant Local Activation permission for the COM
Server application with CLSID
{XXX}
and APPID
Unavailable
to the user XXX SID (XXX) from
address LocalHost (Using LRPC) running in the application container Unavailable SID
(Unavailable). This security permission can be modified using the Component Services
Administrative tool.
Refer to Technical Documents below for other possible causes:
KB41843: In Strategy Enterprise Manager 9.x, scheduled data load does not run.
KB16366: Scheduled data load does not start in Strategy Enterprise Manager 9.x