In Windows 10, when creating a DSN to Microsoft Access (.accdb) metadata using the Strategy Connectivity Wizard, users get the following error:
An error occurred while creating the DSN:Error in Saving the DSN:RegistrySubKeys::OpenSubKey - Key not found

The error happens because the 64-bit Windows 10 system does not come with the 32-bit Access driver. To resolve the error, do the following:

Take the Administration for Enterprise Analytics (10.311) course to learn more about establishing connectivity with the data sources in the Strategy Analytics platform environment.
KB438505