SYMPTOM:
When using the Command Manager script to change the “Default Content Alignment (Presentation Mode Only)” web preference, the preference in Strategy Web is not changed accordingly.
STEPS TO REPRODUCE:

APPLY WEBPREFERENCES NAME "Default Content Alignment (Presentation Mode Only):” VALUE "1” TO PROJECT "Strategy Tutorial";

CAUSE:
This is a known issue in Strategy Web 10.10 and above.
ACTION:
Currently this issue is being reviewed by our Technology team. Strategy will continue to investigate and post updates as soon as they are available.
WORKAROUND:
Change the preference using the dropdown in Strategy Web.
KB440906