After upgrading to Strategy 2020 Update 2 or Strategy 2019 Update 8, the email device with Smart Host mode requires the SMTP server to support the TLS transport protocol.
For more details, refer to KB484645: Email delivery fails with error, "STARTTLS is required but hose does not support STARTTLS".
Strategy.com(you do not need to input the full email address). Leave the rest of the options as default, as shown in the below screenshot.


TLS successfully started on this server" and "
STARTTLS command works on this server" is noticed, as shown in the below screenshot.

Trying TLS on us-smtp-inbound-2.mimecast.com[205.139.110.141.25]